MiSPU - Microbiome Based Sum of Powered Score (MiSPU) Tests

There is an increasing interest in investigating how the compositions of microbial communities are associated with human health and disease. In this package, we present a novel global testing method called aMiSPU, that is highly adaptive and thus high powered across various scenarios, alleviating the issue with the choice of a phylogenetic distance. Our simulations and real data analysis demonstrated that aMiSPU test was often more powerful than several competing methods while correctly controlling type I error rates.

Last updated 7 years ago

openblascpp

4.66 score 8 stars 19 scripts 143 downloads

GLMaSPU - An Adaptive Test on High Dimensional Parameters in Generalized Linear Models

Several tests for high dimensional generalized linear models have been proposed recently. In this package, we implemented a new test called aSPU for high dimensional generalized linear models, which is often more powerful than the existing methods in a wide scenarios. We also implemented permutation based version of several existing methods for research purpose. We recommend users use the aSPU test for their real testing problem.

Last updated 7 years ago

openblascpp

2.70 score 1 stars 5 scripts 116 downloads

prclust - Penalized Regression-Based Clustering Method

Clustering is unsupervised and exploratory in nature. Yet, it can be performed through penalized regression with grouping pursuit. In this package, we provide two algorithms for fitting the penalized regression-based clustering (PRclust) with non-convex grouping penalties, such as group truncated lasso, MCP and SCAD. One algorithm is based on quadratic penalty and difference convex method. Another algorithm is based on difference convex and ADMM, called DC-ADD, which is more efficient. Generalized cross validation and stability based method were provided to select the tuning parameters. Rand index, adjusted Rand index and Jaccard index were provided to estimate the agreement between estimated cluster memberships and the truth.

Last updated 8 years ago

cpp

2.70 score 6 scripts 174 downloads