Package: MiSPU 1.0

Chong Wu

MiSPU: Microbiome Based Sum of Powered Score (MiSPU) Tests

There is an increasing interest in investigating how the compositions of microbial communities are associated with human health and disease. In this package, we present a novel global testing method called aMiSPU, that is highly adaptive and thus high powered across various scenarios, alleviating the issue with the choice of a phylogenetic distance. Our simulations and real data analysis demonstrated that aMiSPU test was often more powerful than several competing methods while correctly controlling type I error rates.

Authors:Chong Wu, Wei Pan

MiSPU_1.0.tar.gz
MiSPU_1.0.zip(r-4.7)MiSPU_1.0.zip(r-4.6)MiSPU_1.0.zip(r-4.5)
MiSPU_1.0.tgz(r-4.6-x86_64)MiSPU_1.0.tgz(r-4.6-arm64)MiSPU_1.0.tgz(r-4.5-x86_64)MiSPU_1.0.tgz(r-4.5-arm64)
MiSPU_1.0.tar.gz(r-4.7-arm64)MiSPU_1.0.tar.gz(r-4.7-x86_64)MiSPU_1.0.tar.gz(r-4.6-arm64)MiSPU_1.0.tar.gz(r-4.6-x86_64)
MiSPU_1.0.tgz(r-4.6-emscripten)
manual.pdf |manual.html
card.svg |card.png
MiSPU/json (API)

# Install 'MiSPU' in R:
install.packages('MiSPU', repos = c('https://chongwu-biostat.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/chongwu-biostat/mispu/issues

Uses libs:
  • openblas– Optimized BLAS
  • c++– GNU Standard C++ Library v3
Datasets:
  • dd - The estimate of Dirichlet-multinomial distribution
  • throat.meta - Meta data of the throat microbiome samples.
  • throat.otu.tab - OTU count table from 16S sequencing of the throat microbiome samples.
  • throat.tree - UPGMA tree of the OTUs from 16S sequencing of the throat microbiome samples.

On CRAN:

Conda:

openblascpp

4.80 score 10 stars 21 scripts 46 downloads 6 mentions 6 exports 22 dependencies

Last updated from:baeb8678fa. Checks:11 NOTE, 2 OK. Indexed: yes.

TargetResultTimeFilesSyslog
linux-devel-arm64NOTE140
linux-devel-x86_64NOTE142
source / vignettesOK179
linux-release-arm64NOTE169
linux-release-x86_64NOTE139
macos-release-arm64NOTE174
macos-release-x86_64NOTE282
macos-oldrel-arm64NOTE178
macos-oldrel-x86_64NOTE364
windows-develNOTE161
windows-releaseNOTE198
windows-oldrelNOTE249
wasm-releaseOK102

Exports:correspLeavesGUniFracMiSPUrankingrdirichletsimulateData

Dependencies:apeaSPUclusterdigestdotCall64fieldsgeelatticemapsMASSMatrixmatrixStatsmgcvmvtnormnlmepermuteRColorBrewerRcppRcppArmadillospamveganviridisLite